The Belgium worldwide has admitted to bulking up for last summer's World Cup and Solskjaer was asked whether the striker needed to shed a little more given the way the United boss wants to play.
The 25-year-old has endured an underwhelming second campaign at Old Trafford, scoring just nine times in 33 appearances.
Jesse Lingard, Ander Herrera and Juan Mata suffered hamstring injuries during the first half at Old Trafford, while Marcus Rashford picked up a ankle problem, with the swelling so severe that he was unable to get his shoe on after the game.
Solskjaer was forced to make three substitutions before half-time on Sunday, including bringing Lingard on and then off again, leaving United with the bare bones to cope with three games in six days. He actually made his first-team debut against Palace on the final day of the 2016/17 season, when he became the first player born in the 2000s to play in the Premier League.
"We ask our forwards, strikers to work at a higher intensity, to run in behind, but that's what he likes, so I'm sure he'll be fine", Solskjaer said.
"It's a chance for them to play to their potential", he said.
"Big teams like Bayern and Manchester United are full of world-class stars and they changed their way of playing to try to stop us".
"Juve have a great project in place and they just keep going".
Robertson was understandably keen to focus on the positive aspects, though, especially given United's approach on Sunday was a similar sign of respect to the one showed by Bayern Munich in last week's goalless Champions League draw. We gave too many balls away too cheaply and luckily that didn't cost us.
"I thought we started really well, and we had the momentum", full-back Robertson said.
Crystal Palace vs Manchester United will be played on Wednesday 27th February at 20:00 GMT. "Muscle is not so hard to get rid of".
"Play well when he gets a chance, keep on training as he does, keep working", Solskjaer said when asked what the Brazil worldwide needs to do.
In a cagey match in which the teams' top players failed to perform, United had less possession but created the best openings.