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The latest and final break up is coming on the heels of news that Thompson allegedly cheated on Khloe with Jordyn Woods, Kylie Jenner's BFF since childhood.

As for these current rumours, Thompson tweeted that the story is "fake news" but has since deleted the post and Woods has yet to respond.

A source told ET on Tuesday that Khloe and Tristan broke up due to ongoing "trust issues" after more than two years of dating and 10 months after the 27-year-old National Basketball Association star made headlines when he reportedly cheated on her with multiple women while she was pregnant with their daughter, True.

Khloe Kardashian has reportedly called it quits with boyfriend Tristan Thompson following another cheating incident.

On Tuesday, Hollywood Unlocked reported that Thompson and Woods were seen at a party with Thompson's house.

In case you've been sleeping under a very peaceful rock, far away from Instagram and Twitter, you should know that Tristan Thompson and Khloe Kardashian have officially broken up.

Kylie replied: 'I promise to encourage you, inspire you, love you, through all the good and bad times'.

"They aren't speaking", a source tells Us.

"Jordyn came in, y'all were smoking hookah, she was all up in your lap".

Perhaps the biggest piece to the puzzle is that Khloe Kardashian actually commented on Jordyn's Instagram photo from two days ago.

Kardashian's best friend Malika Haqq then commented on the post, writing in all capital letters, "STRONG FACTS", while sister Kim Kardashian liked the Instagram post.

Tristan had gone to Los Angeles in order to spend his Valentine's Day with Khloe and their daughter True.

"These hoes ain't loyals", she commented on a video of Kylie's daughter Stormi which had the caption: "Stormi in Calabasas waiting for Jordyn to pack her sh*t and get out of Stormi's house". Kylie Jenner is yet to give her reaction regarding the whole matter.

The Kardashian family's longtime friend Larsa Pippen also commented, "Amen!"

The source added that cutting ties with Woods will be the most hard for Jenner, claiming the Kylie Cosmetics founder "was in denial for days" and "is very torn on how to handle the situation".