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While the Trump Administrations re-imposed sanctions on Iran, Israeli pundits and politicians expressed hope that the new measures would ultimately lead to the downfall of the Islamic Republic. Under the accord, Iran agreed to limit its sensitive nuclear activities and allow global inspections in return for the lifting of crippling economic sanctions.

Trump has said he is ready to hold talks with Iranian leaders, without preconditions but meanwhile, his administration has vowed to press on with its pressure campaign.

Former Iranian diplomat and political commentator Mehrdad Khonsari tells VOA he does not think the protests represent an "existential threat" to the regime, but the new USA sanctions are undoubtedly "placing a good deal of pressure on the government", said Khonsari.

Treier said many of Germany's trading partners were affected by the US measures and their effects, which was, in turn, hurting business with German companies.

"The Iran sanctions have officially been cast".

Iranian President Hassan Rouhani, speaking in a meeting with North Korea's foreign minister, said that America could not be trusted, according to the Islamic Republic News Agency.

Concern over that cyber threat has been rising since May, when Trump pulled out of the 2015 nuclear deal, under which the USA and other world powers eased economic sanctions in exchange for curbs on Iran's nuclear program. "But now, all the countries in the world are supporting Iran".

Iran's foreign minister has said the United States will not be able to prevent the country from exporting oil.

On Tuesday, the USA reinstated sanctions targeting the Iranian government's purchase of U.S. dollars, Iran's trade in gold and other precious metals, and its automotive sector.

In a desperate bid to save the nuclear accord, European governments have pledged to do what they can to keep business links with Tehran. "And it's a good way to show their capacity to inflict economic cost against the United States".

Recorded Future's Moriuchi anticipated that businesses most at risk were those victimized in Iranian cyberattacks between 2012 and 2014 - they include banks and financial services, government departments, critical infrastructure providers, and oil and energy.

More sanctions targeting Iran's oil and gas industry are due to begin in November.

Iranian Foreign Minister Mohammad Javad Zarif told reporters that the global reaction to Trump's move showed that the United States was diplomatically isolated.

After the first batch of USA sanctions on the Islamic Republic entered into force on Tuesday morning, a website affiliated to Iran's Supreme Leader Ali Khamenei said on Wednesday that there was nothing for Tehran to worry about. "They can't think that Iran won't export oil and others will export".

"Iran must know that Washington is determined to send a powerful message that its aggressive, bellicose behavior must change dramatically, or else it faces serious economic consequences", he continued.

He urged the German government to provide details on how it would protect German firms after the latest US sanctions against Iran, adding that if Berlin did not do that, German firms would gradually cease doing business there.