When asked if he is targeting a fight against British opponent Kell Brook, Khan added: "I want to become a world champion again so I want to fight the top guys in the welterweight division".
Four months after facing snakes and spiders in an Australian jungle, Amir Khan returns to the limelight in a more comfortable arena determined to end his boxing career on a high.
When Khan resumed his attack with fast and furious punches, Lo Greco folded on the ropes and the fight was waved off.
This was Khan's first in a three-fight deal with promoter Eddie Hearn, who also works with Brook.
The 31-year-old will have a British homecoming fight against Lo Greco in Liverpool this Saturday night, live on Sky Sports, and a victory could line up a big domestic battle with Brook. "There are a lot of people who I could fight against in the United Kingdom after so long, and the last couple fights have been in America, I think, just to hype people to see me back here". Kell Brook has been living off my name for a long time.
"My hand eye co-ordination was very, very sharp".
Whether, after almost two years out of competitive action, he still has the speed and technique to shield his fragile chin is the question fight fans will want answered. I saw the opening and finished him off. It's a big fight for the Brit in Liverpool, too, not just because of his two years out of the ring.
"I came to do a clinical job and be smart and show good movement. When he gets in there with me, I'll make him see stars!"
"I want to thank all the fans for turning out and enjoying my victory. I came and signed with Matchroom, I'm the one chasing Kell".
Brook responded: "He doesn't want the fight".
Brook was ringside to run the rule over Khan at the Echo Arena.
"This fight should have happened 12 moths ago, two years ago, we have still got time", Hearn said.