Larger than models from previous years, the Accord edged out the Toyota Camry and the Kia Stinger for the honor presented in Detroit.
Juror Ron Sessions of the New York Daily News said, the 2018 Navigator "received a more dramatic update than its Ford Expedition sibling and its impact for the brand will be stronger as a result".
The North American Truck of the Year was Lincoln's all-new Navigator.
Gary Gastelu is FoxNews.com's Automotive Editor.
Auto experts called the newly redesigned Accord the best iteration of its 41-year history, with sleeker styling and a roomier interior as well as a turbo-charged engine, CNN Money reported.
The Navigator, itself, closed 2017 with a 30.1-percent year-over-year increase in December sales.
The brand sold only 10,523 Navigators past year, far behind competitors in the segment such as the Cadillac Escalade. Eligible vehicles, chosen from dozens, must be new or substantially changed. Each judge was charged with evaluating the contenders based on factors including innovation, design, safety, performance, technology, driver satisfaction and value.
The Honda Ridgeline truck won truck of the year in 2017, and the Civic won vehicle of the year in 2016, CNN Money reported.
Organizers accept no advertising, though automakers try to capitalize on the marketing value of the awards.