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The Leader also referred to Trump's remarks against the nuclear deal between Tehran and world powers, known as Joint Comprehensive Plan of Action (JCPOA), and Europe's support for Iran on this issue.

"I don't want to waste time on answering the rants and whoppers of the brute U.S. president", Ayatollah Ali Khamenei said.

Reacting to President Trump's decertification of the nuclear deal and threats to walk away from it, Ayatollah Khamenei stressed that "if U.S. rips up the deal, Iran will tear it into shreds".

Trump said that "in the event we are not able to reach a solution, working with Congress and our allies, then the agreement will be terminated".

He also said that his new strategy begins with imposing tough sanctions on the IRGC, accusing Iran of "proliferation of missiles and weapons that threaten its neighbor's global trade and freedom of navigation".

“If Iran is compliant, if the European Union and China and Russian Federation continue to consider that the JCPOA (Joint Comprehensive Plan of Action) can be applied, then that means the US would have to take unilateral sanctions.,” Pouyanne said in the interview published on Tuesday.

But Washington has accused Iran of "malign activities" across the Middle East, including a recent missile test.

Supporters of the deal fear Trump's decision to decertify the deal could eventually unravel it, causing more tension in the crisis-hit Middle East, where Shi'ite Iran is involved in a decades long proxy war with USA ally Sunni Saudi Arabia. If that were to happen, the U.S. would in effect be in violation of the terms. "It is a waste of time to respond to such a person".

He said Mr Trump was "mad" because Iran was spoiling USA "plots" in Lebanon, Syria, Iraq and Egypt, according to an account of the meeting with the students that was posted on his official website.

The Leader further hit back at Trump's anti-Iran allegations and said US President Donald Trump shows stupidity, but this should not distract Iran from the Americans' deceitfulness.

The senior commander went on to say that not only European countries and the International Monetary Fund (IMF) refused to comply with Trump's stance toward Iran, but even his own defense and state secretaries held him in contempt for such a stance.

Israelis with an inside track on the Iran deal have reacted positively to Trump's latest position.

Senior officials in France, Britain and Germany have dismissed the United States president's approach to the JCPOA, saying they will continue to support the nuclear deal.

"Europe must stand against practical measures (taken) by America", he said. "Why do YOU have nuclear weapons?"