It was Chelsea's fourth successive win over Spurs at the national stadium - the previous three were in cup games - and hardly bodes well for Tottenham's temporary home while their new stadium is being built.
It was Pochettino's first home league defeat in 14 London derbies.
"I think we did great in a clever way".
"It is something that is spoken about a lot but I am not too bothered by it", he said.
"It's not fair to blame Wembley".
The defensive nature of Conte's line-up illustrated that the Blues knew that Tottenham posed a big attacking threat, while the visitors were short on forward-thinking players.
But despite a roaring atmosphere at the Wembley that made it feel like home, Tottenham failed to break the hoodoo.
Michy Batshuayi's own goal had just six minutes earlier cancelled out Alonso's first-half free-kick.
Hazard tears into Chelsea tactics after win v Tottenham
"I'm disappointed because we deserved more but they were very clinical with two shots on target and two goals", the 45-year-old Argentine told the BBC. "They put in a good performance against a really good Tottenham team". In truth, it would seem foolhardy now in hindsight to suggest that the Blues could find a player better to fulfil his role.
However, on the attacking front Alonso easily has the lead - particularly in goals scored.
Marcos Alonso was the star of the show as he scored twice for Chelsea to record their first win over the season. "For us, it was hard to score".
Chelsea head coach Conte afterwards lauded his "fighters".
It is two wins out of two and two clean sheets for a Huddersfield team playing in the top flight for the first time since 1972 " two decades before the inception of the Premier League. "I am very pleased with the will to fight for every ball and they showed me the desire of last season is still there. this is a ideal response of the champions". I saw a lot of positive things in a moment that's not easy for us with the suspensions and the injuries.
"When you see the team sheets at the start, and compare them to last season, Spurs will be kicking themselves they didn't get the result".
"You thought today before the game, this was more than three points for Chelsea because you could see if they were beaten here today and beaten well it could start to unravel a little bit".
"We showed great desire to stay compact, not lose the balance".