Since Thursday there have been back-and-forth tweets between Trump and the hosts of MSNBC's morning television show "Morning Joe". "I think that the president has been attacked mercilessly on personal accounts by members on that programme, and I think he's been very clear that when he gets attacked, he's going to hit back", she told the daily White House briefing.
He also said that the "fake and fraudulent" media is working hard to convince Republicans and others he should not use the social media. But he called Scarborough "crazy" and Brzezinski "dumb as a rock". "It's about time!" he tweeted, referring to an article that the cable news channel retracted, that claimed Congress was investigating links between Trump's administration and a Russian investment fund.
The duo's row with the President escalated further on Friday when Mr Trump denied their claim that senior White House staff warned them earlier this year the National Enquirer tabloid was planning a negative story about them.
Trump also escalated his war with media at an event to honour USA military veterans ahead of July 4, the American Independence Day.
Maher also had a suggestion for "whoever is doing the babysitting lately": get Trump a toy smart phone designed for children 18 months and older.
Added Scarborough, "He's so much worse with women".
Both Democratic and Republican lawmakers condemned Trump's tweets, and some have urged him to stop tweeting altogether.
Ms Brzezinski in recent weeks has wondered whether Mr Trump was mentally ill and said the country under his presidency "does feel like a developing dictatorship".
The shocking tweet is presumed to be a response to a segment the show did that morning which took aim at a fake Time magazine cover featuring Trump that hangs at several of Trump's golf clubs and properties, according to The Washington Post.
In a Washington Post op-ed, Mika and Joe said she "never had a face-lift", as the President claimed, but did admit that she had "a little skin under her chin tweaked, but this was hardly a state secret".